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Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis
a cyclic AMP-specific PDE (PDE 4) inhibitor (10 mM) and by cyclic GMP-elevating agents (50 nM ANF or 30 nM SNP plus 100 nM DMPPO)
InChi: InChI=1S/C15H10Cl2N2O2S/c1-21-13-7-12(9(16)6-10(13)17)19-14(20)8-4-2-3-5-11(8)18-15(19)22/h2-7H
InChi: InChI=1S/C15H24N2O2
and displays marked anti-tumor efficacy in KRAS mutant xenografts
Melflufen hydrochloride - CAS# 380449-54-7 Size:10mg solid Glycochenodeoxycholic acid sodium salt (ChenodeoxycholylglycineMelflufen (Melphalan flufenamide) hydrochloride, a dipeptide prodrug of Melphalan, is an alkylating agent. Melflufen hydrochloride shows antitumor activity against multiple myeloma (MM) cells and inhibits angiogenesis. Melflufen hydrochloride induces irreversible DNA damage and cytotoxicity in MM cells. Product information CAS Number: 380449 54 7 Molecular Weight: 534. 88 Formula: C24H31Cl3FN3O3 Chemical Name: ethyl (2S) 2 [(2S) 2 amino 3 {4 [bis(2