O-1602 Catalog No.:M22717-C CAS Number: 1207989-09-0

CAS Number: 1207989-09-0

C2H4O2/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55

InChiKey: CKUFOBCNTCLXJP-UHFFFAOYSA-N

InChi: InChI=1S/C21H18O12/c22-9-2-1-7(3-10(9)23)13-6-12(25)15-11(24)4-8(5-14(15)32-13)31-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6

Caerulomycin)

O-1602 Catalog No.:M22717-C CAS Number: 1207989-09-0O 1602 is an agonist of GPR55 (EC50 = 13 nM in a GTPS binding assay) and a derivative of the GPR55 agonist abnormal cannabidiol. It is selective for GPR55 over cannabinoid (CB) receptor 1 (CB1) and CB2 (EC50s = >30 M for both in GTPS binding assays). O 1602 (50 M) reduces growth of Mz ChA 1, HuCCT 1, CC LP 1, and SG231 cholangiocarcinoma cells and reduces tumor growth in a Mz ChA 1 mouse xenograft model when administered at a dose of 10 mg kg per day.