NVR 3-778 eline 2-6H3/b17-15+

2-6H3/b17-15+

InChi: InChI=1S/C20H13F6NO4/c1-30-17-7-11(6-13(9-27)18(28)29)2-5-16(17)31-10-12-3-4-14(19(21

is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 µM

FGF401 binds to and inhibits the activity of FGFR4

1977 Jan 6

NVR 3-778 eline 2-6H3/b17-15+NVR 3 778 is a first in Class and oral bioavailable HBV CAM (capsid assembly modulator) belonging to the SBA (sulfamoylbenzamide) class, with anti HBV activity. Product information CAS Number: 1445790 55 5 Molecular Weight: 432. 39 Formula: C18H16F4N2O4S Chemical Name: 4 fluoro 3 [(4 hydroxypiperidin 1 yl)sulfonyl] N (3,4,5 trifluorophenyl)benzamide Smiles: OC1CCN(CC1)S(=O)(=O)C1=CC(=CC=C1F)C(=O)NC1=CC(F)=C(F)C(F)=C1 InChiKey: KKMFSVNFPUPGCA