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a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo
with mean IC50 potency less than 15 nM
]henicosa-1
VR23 was structurally distinct from other known proteasome inhibitors and selectively killed cancer cells by apoptosis
Am J Clin Dermatol
Cortisone 4286 a novel small-molecule mer inhibitorCortisone (17 Hydroxy 11 dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid receptor at high concentrations. Product information CAS Number: 53 06 5 Molecular Weight: 360. 44 Formula: C21H28O5 Chemical Name: (1R,3aS,3bS,9aR,9bS,11aS) 1 hydroxy 1 (2 hydroxyacetyl) 9a,11a
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