amyloid P-IN-1 is used in the research of diseases or disorders wherein depletion of serum amyloid P component (SAP)
especially the alpha-1 subunit
which inhibits ATR immunoprecipitated from HeLa nuclear extracts with an IC50 of 5 nM and ATR mediated phosphorylation of Chk1 in HT29 colorectal adenocarcinoma tumor cells with an IC50 of 50 nM
Chemical Name: N-(2-{3-[(piperazin-1-yl)methyl]imidazo[2
3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide InChI Key
D-Ribonolactone Catalog No.:M14761-2 amyloid P-IN-1 is used inD Ribonolactone is sugar lactone and an inhibitor of galactosidase of Escherichia coli with a Ki of 26 mM. Product information CAS Number: 5336 08 3 Molecular Weight: 148. 11 Formula: C5H8O5 Chemical Name: (3R,4S,5R) 3,4 dihydroxy 5 (hydroxymethyl)oxolan 2 one Smiles: OC[C@H]1OC(=O)[C@H](O)[C@@H]1O InChiKey: CUOKHACJLGPRHD BXXZVTAOSA N InChi: InChI=1S C5H8O5 c6 1 2 3(7)4(8)5(9)10 2 h2 4,6 8H,1H2 t2 ,3 ,4 m1 s1 Technical Data Appearance: Solid Power