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18-dimethoxy-17-(3
3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)butoxy)butoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1
AK-7 treatment resulted in improved motor function
Formula: C25H19NO3S
IC87114 (10 µM) inhibits both constitutive and Flt-3-stimulated Akt phosphorylation and cell proliferation
VER-49009 Size:Solid 10 mg 18-dimethoxy-17-(3VER 49009 is a potent HSP90 inhibitor. VER 49009 inhibits Hsp90 with an IC50 value of 47 nM. VER 49009 produces a cellular antiproliferative GI50 value of 685 nM when tested against a human cancer cell line panel. Consistent with inhibition of Hsp90, VER 49009 induces the expression of Hsp27 and Hsp72 while reducing the client proteins C RAF, B RAF, survivin, and PRMT5, causing cell cycle arrest and apoptosis. Product information CAS Number: 558640 51
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