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Targeting BET Bromodomains
30)27-15-4-5-15)6-7-18(19)13-8-9-31-12-13/h1-3
CNV-1014802
[Epub ahead of print] PubMed PMID: 31087357
a new potential PET agent for imaging of glycogen synthase kinase-3 (GSK-3)
Gefitinib-based PROTAC 3 - CAS# 2230821-27-7 size:10mg solid Targeting BET BromodomainsGefitinib based PROTAC 3, CAS No. 2230821 27 7, also known as Gefitinib based PROTAC 3 is a VHL recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11. 7 nM and 22. 3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R). Product information CAS Number: 2230821 27 7 Molecular Weight: 934. 51 Formula: C47H57ClFN7O8S Synonym: Gefitinib based PROTAC 3 NTN21277 NTN 21277 NTN 21277 Chemical Name: (2S,4R) 1 ((S) 2 (3 (2