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LY2606368 may potentiate the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapeutic agents
6-dimethylphenyl)-4-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-1
Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin
L-Moses binds in the acetylated lysines (KAc) -binding pocket of PfGCN (blue ribbon and sticks) and makes H-bonds (dotted lines) through the triazole to N1436 and the first of a network of four water molecules (red spheres)
PubMed PMID: 23692254
Syk-IN-3 Catalog No.:M15130-2 LY2606368 may potentiate the cytotoxicitySyk IN 3, a potent spleen tyrosine kinase (Syk) inhibitor, extracted from patent WO2011075515A1, compound example 152, has an IC50 of 1 nM. Product information CAS Number: 1312534 69 2 Molecular Weight: 452. 57 Formula: C24H28N4O3S Chemical Name: (1S,4R) 4 hydroxy 2,2 dimethyl 4 (5 {3 methyl 5 [(4 methylpyrimidin 2 yl)amino]phenyl} 1,3 thiazol 2 yl)cyclohexane 1 carboxylic acid Smiles:
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