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IC50 Value: 27±5 nM(Ki) Target: 5-HT1A in vitro: Tandospirone is most potent at the 5-HT1A receptor
αvβ8 and α5β1
Expert Opin Drug Discov
Ph+ human ALL xenografts responds to FTY720 with an 80 % reduction in overall disease if treatment has been initiated early on
The preliminary results in a U87GM xenograft model have shown that PFK-015 has comparable activity to Temozolomide
EHT 5372 Catalog No.:M16773-C IC50 Value: 27±5 nM(Ki) Target:EHT 5372 is a highly potent and selective inhibitor of DYRKs family kinases with IC50s of 0. 22, 0. 28, 10. 8, 93. 2, 22. 8, 88. 8, 59. 0, 7. 44, 221 nM for DYRK1A, DYRK1B , DYRK2 DYRK3 CLK1, CLK2, CLK4, GSK 3, GSK 3. Product information CAS Number: 1425945 63 6 Molecular Weight: 404. 27 Formula: C17H11Cl2N5OS Chemical Name: methyl 9 [(2,4 dichlorophenyl)amino] [1,3]thiazolo[5,4 f]quinazoline 2 carboximidate Smiles:
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