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and 50 microg/ml
In one of the clinical trials
ACT 132577
CAS Number: 872573-93-8
21561-09-1
CDK9-IN-1 - CAS# 1415559-43-1 pazide Maleate and 50 microg/mlCDK9 inhibitor is a small molecule selective inhibitor of CDK9 (cyclin dependent kinase 9) with IC50 value of 39 nM. CDKs are a group of serine threonine kinases and are widely spread in all known eukaryotes. CDKs are activated through binding to cyclins and forming heterodimers. In the dimer, CDK acts as a catalytic subunit and phosphorylates the down stream proteins such as nuclear lamina protein, nucleolin and histone H1. Through this way, CDKs
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