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75% of total content with 10 μM 22 vs 8
structural analysis and mutagenesis
The half-life of 5-8 h and an AUC0
Formula: C12H7F2NO3S2
Miyamoto T
ESI-09 - CAS# 263707-16-0 size:2mg solid 75% of total content withESI 09, CAS No. 263707 16 0, is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intracellular EPAC mediated Rap1 activation and Akt phosphorylation, as well as EPAC mediated insulin secretion in pancreatic cells. EPAC1 plays an important role in pancreatic cancer cell migration and invasion, and thus represents a potential target for developing novel therapeutic strategies for pancreatic cancer. Product
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