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PT2399 has greater activity than sunitinib
The values of IC50 were 29 and 15 μg/ml
SB-590885 is a novel triarylimidazole that selectively inhibits Raf kinases with more potency towards B-Raf than c-Raf
Smiles: COC1=CC(=CC=C1)[C@@H](C)NC(=O)C1C=CC(=CC=1)C1C=CN=CC=1
UNC6852 has no cytotoxicity when the concentration of HeLa cells is up to 30 μM
Salidroside(Rhodioloside) F-04217903 PT2399 has greater activity thanSalidroside is a prolyl endopeptidase Inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1 Parkin mediated mitophagy. Product information CAS Number: 10338 51 9 Molecular Weight: 300. 30 Formula: C14H20O7 Synonym: Rhodioloside Chemical Name: (2R, 3S, 4S, 5R, 6R) 2 (hydroxymethyl) 6 [2 (4 hydroxyphenyl)ethoxy]oxane 3, 4, 5