JNK-IN-7 - CAS# 1408064-71-0 amin PF-CBP1 reduces LPS-induced IL-1β

PF-CBP1 reduces LPS-induced IL-1β

Crawford ED

It has IC50 of 2

NSC 609669

The agent may enhance expression of the TGFβ-1 gene in a fashion analogous to that demonstrated for CsA

JNK-IN-7 - CAS# 1408064-71-0 amin PF-CBP1 reduces LPS-induced IL-1βJNK IN 7 is a relatively selective JNKs inhibitor(IC50= 1. 54 1. 99 0. 75 for JNK1 2 3); also bound to IRAK1, PIK3C3, PIP5K3 and PIP4K2C. Product information CAS Number: 1408064 71 0 Molecular Weight: 493. 56 Formula: C28H27N7O2 Synonym: JNK inhibitor Chemical Name: 3 [(2E) 4 (dimethylamino)but 2 enamido] N (4 {[4 (pyridin 3 yl)pyrimidin 2 yl]amino}phenyl)benzamide Smiles: CN(C)C C=C C(=O)NC1=CC(=CC=C1)C(=O)NC1C=CC(=CC=1)NC1=NC(=CC=N1)C1=CN=CC=C1