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PF-670462 shows less than 30-fold selevtivity for EGFR and SAPK2A/p38
Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner
Echinacoside inhibits breast cancer cells by suppressing the Wnt/β-catenin signaling pathway
Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel
ABT-888 dihydrochloride is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5
Gatifloxacin Catalog No.:M10548-10 PF-670462 shows less than 30-foldGatifloxacin is an antibiotic of the fourth generation fluoroquinolone family that inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Gatifloxacin is a fluoroquinolone antibiotic, with potent activity against Gram negative and Gram positive bacteria. Bristol Myers Squibb introduced Gatifloxacin in 1999 under the proprietary name Tequin for the treatment of respiratory tract infections. Allergan produces it in eye drop formulation under