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(Rac)-Calpain Inhibitor XII inib bromide RITA (1 μM) stabilizes p53

SKU: 25841508155

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Description

RITA (1 μM) stabilizes p53 by inhibiting p53/E6AP interaction

EMPA inhibits orexin-A-or orexin-B-evoked [Ca2+]i response with IC50s of 8

2018 Dec 21

CAS Number: 29849-82-9

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma

(Rac)-Calpain Inhibitor XII inib bromide RITA (1 μM) stabilizes p53(Rac) Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I ( calpain, Ki=19 nM). (Rac) Calpain Inhibitor XII has lower affinities for calpain II (m calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac) Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Product information CAS Number: 181769 57 3

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