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CDK8/19i Catalog No.:M7562-2 9 nM (IC50s)for PDE1B in

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Description

9 nM (IC50s)for PDE1B in vitro (43

Smiles: CC1C(=C(SC=1C1C=CC(Cl)=CC=1)C(=O)CC)C1C=CC(=CC=1)S(N)(=O)=O

T cell proliferation in response to ligation of the T cell receptor is inhibited by Tacrolimus

677331-12-3

is an iron chelator

CDK8/19i Catalog No.:M7562-2 9 nM (IC50s)for PDE1B inCDK8 19i is a potent and selective CDK8 and CDK19 inhibitor (IC50 values are 2. 9 and 14. 1 nM, respectively). CDK8 19i maintains pluripotency of mouse PSCs in culture. It induces the formation of dome shaped colonies and upregulates Nanog GFP reporter and endogenous Nanog expression in mouse ESCs in vitro. Product information CAS Number: 923596 52 5 Molecular Weight: 253. 30 Formula: C14H15N5 Chemical Name: N propyl 3 (pyridin 4 yl)imidazo[1,2

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