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Surapaneni S
reduces grip strength of the forelimbs and increased distance between the hind limbs in the landing foot-splay test)
Pretreatment with tangeretin inhibites IL-1beta-induced p38 MAPK
CAS Number: 1168091-68-6
NSC59984 as a promising lead compound for anticancer therapy that acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling
PJ34 - CAS# 344458-19-1 e O-desmethyl Mebeverine acid Surapaneni SPJ 34 is a novel and potent PARP 1 inhibitor with potential anticancer activity. PJ34 has a high affinity for PARP 1 (IC(50) = 20 nM). PJ 34 inhibits PARP 1 expression and ERK phosphorylation in glioma conditioned brain microvascular endothelial cells. PJ 34 reduces mesenteric vascular injury induced by experimental cardiopulmonary bypass with cardiac arrest. PJ 34 reduce cell inflammation and damage that follow PARP 1 overexpression. PJ 34 negatively