HS-131 nel RG14620 is an EGFR inhibitor

RG14620 is an EGFR inhibitor with an IC50 of 3 μM

6) with activity at rat (pK(i) = 7

Obtusifolin isolated from the seeds of Cassia obtusifolia regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via affecting NF-κB pathway

1 nM (BRD2 BD1)

Due to its high lipophilicity

HS-131 nel RG14620 is an EGFR inhibitorHS 131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene driven breast cancers, including multiple different molecular subtypes of human breast cancers. Product information CAS Number: 2084850 40 6 Molecular Weight: 1318. 68 Formula: C71H95N7O13S2 Chemical Name: 2 [(1E, 3Z) 3 [4 (21 {[2 carbamoyl 5 (3, 6, 6 trimethyl 4 oxo 4, 5, 6, 7 tetrahydro 1H indazol 1 yl)phenyl]amino} 6, 9, 12, 15, 18 pentaoxa 2 azahenicosan 1 yl)phenyl]