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In multiple myeloma (MM) cells
Smiles: CN(C)C1=CC2=[O+]C3=CC(=CC=C3C(C3=CC=C(C=C3C([O-])=O)C(O)=O)=C2C=C1)N(C)C
InChi: InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8
m-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
InChi: InChI=1S/C154H244N48O29/c1-18-87(11)121-141(226)190-108(73-84(5)6)131(216)188-112(78-118(206)207)136(221)199-153(16
Vincristine domide-Propargyne-PEG3-COOH In multiple myeloma (MM) cellsVincristine (Leurocristine, NSC 67574, 22 Oxovincaleukoblastine) is a natural alkaloid isolated from the plant Vinca rosea Linn. with anti tumor activity. Vincristine inhibits microtubule formation in mitotic spindle and binds to microtubule with Ki of 85 nM. Product information CAS Number: 57 22 7 Molecular Weight: 824. 96 Formula: C46H56N4O10 Chemical Name: methyl 11 (acetyloxy) 12 ethyl 4 [17 ethyl 17 hydroxy 13 (methoxycarbonyl) 1,11