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Selonsertib free base - CAS# 1448428-04-3 0321 Mefentrifluconazole is not a skin

SKU: 35460717029

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Description

Mefentrifluconazole is not a skin or an eye irritant

Wittko-Schneider IM

HS-173 (10 and 30 mg/kg) significantly decreases the metastatic burdens on the lung and liver

Patterson JN

It has minimal inhibition of UCHL-1

Selonsertib free base - CAS# 1448428-04-3 0321 Mefentrifluconazole is not a skinSelonsertib free base, CAS No. 1448428 04 3, also known as GS 4997, is an orally bioavailable inhibitor of apoptosis signal regulating kinase 1 (ASK1), with potential anti inflammatory, antineoplastic and anti fibrotic activities. GS 4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP competitive manner, thereby preventing its phosphorylation and activation. GS 4997 prevents the production of inflammatory cytokines, down regulates

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