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The DDR1 receptor tyrosine kinase is activated by matrix collagens and has been implicated in numerous cellular functions such as proliferation
Furamidine effectively inhibits intracellular PRMT1 activity and blocks cell proliferation in leukemia cell lines with different genetic lesions
Oseltamivir phosphate (OP) is a prodrug that is readily absorbed from the gastrointestinal tract after oral administration and is extensively converted predominantly by hepatic esterases to Oseltamivir carboxylate (OC)
Formula: C13H11N3O
Therapeutically active compounds and their methods of use
CI-1040 (PD184352) Size:10mg solid The DDR1 receptor tyrosine kinaseCI 1040, also known as PD184352, is a MEK inhibitor, which demonstrated in vivo activity in preclinical animal models and subsequently became the first MEK inhibitor to enter clinical trial. CI 1040 suffered however from poor exposure due to its poor solubility and rapid clearance, and as a result, development of the compound was terminated. Product information CAS Number: 212631 79 3 Molecular Weight: 478. 66 Formula: C17H14ClF2IN2O2 Synonym: CI1040