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5-20 mg/kg once or twice per day to inhibit tumor growth
and induces apoptosis in tumor cell lines
is a novel small molecule that binds to orphan Nuclear Receptor Nur77 with high affinity (Kd = 1
2ClH/c16-12-6-8-13(9-7-12)17-15-10-14(15)11-4-2-1-3-5-11
Chemical Name: 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4
Pirfenidone D5. CAS# 1020719-62-3 size:2mg solid 5-20 mg/kg once or twicePirfenidone D5, CAS No. 1020719 62 3, is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth inhibitory effect and reduces TGF 2 protein levels in human glioma cell lines. Pirfenidone also has anti inflammatory activities. Product information CAS Number: 1020719 62 3 Molecular Weight: 190. 25 Formula: C12H11NO Synonym: IC50 & Target TGF 2 CCL2 and
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