CAS Number: 138489-18-6
InChi: InChI=1S/C40H69N11O14S/c1-20(2)13-26(36(60)43-15-30(54)45-23(6)34(58)46-22(5)33(57)42-16-32(56)48-27(40(64)65)14-21(3)4)49-38(62)29-9-8-11-51(29)39(63)25(10-12-66-7)47-31(55)17-44-37(61)28(19-53)50-35(59)24(41)18-52/h20-29
increasing the bimolecular rate constant for the inhibition of thrombin by a factor of 2000
InChi: InChI=1S/C11H13BrN2O6/c12-2-1-5-3-14(11(19)13-9(5)18)10-8(17)7(16)6(4-15)20-10/h1-3
InChiKey: UEQSLJQFVIWCCW-UHFFFAOYSA-N
Pladienolide B 427Arg)9 CAS Number: 138489-18-6Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre mRNA splicing. Pladienolide B induces apoptosis. Product information CAS Number: 445493 23 2 Molecular Weight: 536. 70 Formula: C30H48O8 Chemical Name: (2S,3S,6S,7R,10R) 7,10 dihydroxy 2 [(2E,4E,6S) 7 [(2R,3R) 3 [(2R,3S) 3 hydroxypentan 2 yl]oxiran 2 yl] 6