Vandetanib - CAS# 443913-73-3 CRABP-II Degrader-1 is a potent MCT inhibitor

is a potent MCT inhibitor

Chemical Name: ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid

26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28

R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies

Inhibition of the c-fms proto-oncogene autocrine loop and tumor phenotype in glucocorticoid stimulated human breast carcinoma cells

Vandetanib - CAS# 443913-73-3 CRABP-II Degrader-1 is a potent MCT inhibitorVandetanib is an orally bioavailable 4 anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGF2), thereby blocking VEGF stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability. This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that mediates tumor cell