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InChi: InChI=1S/C27H29FN2O3/c28-25-18-22(13-11-20(25)12-14-27(31)32)29-19-21-6-4-10-26-24(21)9-5-15-30(26)16-17-33-23-7-2-1-3-8-23/h1-4
InChiKey: PUQSUZTXKPLAPR-UJPOAAIJSA-N
Probe Reports from the NIH Molecular Libra
The (Z)-isomer has been consigned the name BMS-205912
is a selective and cell permeable methyl-lysine binding protein 53BP1 antagonist with micromolar activity
M-110 0192 InChi: InChI=1S/C27H29FN2O3/c28-25-18-22(13-11-20(25)12-14-27(31)32)29-19-21-6-4-10-26-24(21)9-5-15-30(26)16-17-33-23-7-2-1-3-8-23/h1-4M 110 is a inhibitor of protein arginine N methyltransferases (PRMTs). It is also a highly isoform selective, cell permeable and potent ATP competitive inhibitor of the PIM kinase family that prefers PIM 3, shown to inhibit the proliferation of prostate cancer cell lines with IC50s between 0. 6 to 0. 9 M, with no activity on normal human peripheral blood mononuclear cells up to 40 M. Product information CAS Number: 1395048 49 3 Molecular Weight: 445.