SRPIN340 fisoxazole InChi: InChI=1S/C35H28N4O5/c1-35-31(43-3)23(37(2)34(42)18-11-5-4-6-12-18)17-24(44-35)38-21-15-9-7-13-19(21)25-27-28(33(41)36-32(27)40)26-20-14-8-10-16-22(20)39(35)30(26)29(25)38/h4-16

InChi: InChI=1S/C35H28N4O5/c1-35-31(43-3)23(37(2)34(42)18-11-5-4-6-12-18)17-24(44-35)38-21-15-9-7-13-19(21)25-27-28(33(41)36-32(27)40)26-20-14-8-10-16-22(20)39(35)30(26)29(25)38/h4-16

86(5):969-77

KU-57788 is solvent-exposed in BRD4

Smiles: CC1(CCCNC(=O)NCCCC[C@H](N)C(O)=O)N=N1

commonly marketed as its salt brompheniramine maleate

SRPIN340 fisoxazole InChi: InChI=1S/C35H28N4O5/c1-35-31(43-3)23(37(2)34(42)18-11-5-4-6-12-18)17-24(44-35)38-21-15-9-7-13-19(21)25-27-28(33(41)36-32(27)40)26-20-14-8-10-16-22(20)39(35)30(26)29(25)38/h4-16SRPIN340 is a selective serine arginine protein kinase (SRPK) 1 inhibitor with Ki = 0. 89 M. SRPK1 is a common binding partner of the E1^E4 protein of diverse human papillomavirus types. SRPK1 selective inhibitors could be a potentially novel topical (eye drop) therapeutic for wet AMD. Product information CAS Number: 218156 96 8 Molecular Weight: 349. 35 Formula: C18H18F3N3O Chemical Name: N [2 (piperidin 1 yl) 5 (trifluoromethyl)phenyl]pyridine 4