![IWP-2-V2 alidomide-PEG3-iodine 2-dihydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M22354_1635322422.gif?v=1635322424)
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2-dihydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid
C2HF3O2/c21-9-2-1-3-10-22-16(26)11-30-14-6-4-5-12-17(14)20(29)24(19(12)28)13-7-8-15(25)23-18(13)27
respectively)
Smiles: FC1=C2NC(CNC3=NC(=NC4=C(C=NN34)C3CC3)N3CCOCC3)=NC2=CC=C1F
InChi: InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2
IWP-2-V2 alidomide-PEG3-iodine 2-dihydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acidIC50: 27 nM IWP 2 V2 is a Wnt production inhibitor. Wnt signaling proteins are small secreted proteins that are active in tissue homeostasis, embryonic development, and tumorigenesis. Wnt proteins bind to receptors, initiating a signaling cascade that results in catenin activation of gene transcription. In vitro: IWP 2 was identified as an inhibitor of Wnt production inactivating porcupine, a membrane bound O acyltransferase whose palmitoylation
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