HO-3867 is a selective and potent STAT3 inhibitor and shows good antitumor activity
1 to 10 mg/kg) dose-dependently inhibits growth of the primary (ear) and lymph node metastases of B16/BL6 melanoma
Smiles: C[C@]1(O)C[C@H](O[C@@H](COC)C[C@H]2O[C@@](O)([C@H](O)[C@@H]3C[C@H](OC)[C@@H](O)CCC=C(C)C=C[C@@H](O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](O)[C@@H]4O)[C@H](C)C=C(C)C=C(C)C=C(C)C(=O)O3)[C@H](C)[C@@H](O)[C@H]2C)O[C@@H](C)[C@@H]1O[C@H]1C[C@@H](OC)[C@H](O)[C@@H](C)O1 |c:26
Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid
N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)
Cortistatin 14, human, rat - CAS# 193829-96-8 1776 HO-3867 is a selective andCortistatin 14, human, rat (CST 14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co exists with GABA within the cortex and hippocampus. Product information CAS Number: 193829 96 8 Molecular Weight: 1721. 01 Formula: C81H113N19O19S2 Synonym: CST 14, human, rat Chemical Name: (2S) 6 amino 2