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including epilepsy and parkinson's disease
InChi: InChI=1S/C14H16O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-6
High-resolution mass spectrometry-based approach for the identification and profiling of the metabolites of taletrectinib formed in liver microsomes
and CrkL in K562 cells with IC50 values of 170 nM
InChiKey: RAGZUCNPTLULOL-KQJPBSFVSA-N
G-36 8100 including epilepsy and parkinson's diseaseG protein coupled estrogen receptor (GPER), or GPR30, specifically binds natural and man made estrogens. It is thought to be involved in estrogen sensitive cancers., GPER knockout mice are fertile, although they exhibit thymic atrophy, impaired glucose tolerance, and altered bone growth. G 36 is a cell permeable non steroidal antagonist of GPER, inhibiting activation by either 17 estradiol or the GPER selective agonist G 1 (IC50 = 112 and 165 nM,