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with IC50s of 102 ± 19 nM and 276 ± 26 nM
enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats
212141-51-0 (Vatalanib hydrochloride)
4-dihydro-1(2H)-quinolinyl)-2-oxoethoxy]carbonyl]hydrazide
ADX-47273 increased (9-fold) the response to threshold concentration of glutamate (50 nM) in fluorometric Ca(2+) assays (EC(50) = 170 nM) in human embryonic kidney 293 cells expressing rat mGlu5
Scopine Hydrochloride 0185 with IC50s of 102 ±Scopine HCl is a metabolite of the muscarinic antagonist scopolamine. Scopine binds to muscarinic acetylcholine receptors and is selective for muscarinic acetylcholine receptors over nicotinic acetylcholine receptors. It reduces hyperphagia induced by the antipsychotics loxapine and chlorpromazine. When conjugated to chlorambucil, scopine improves the blood brain barrier permeability of chlorambucil. Product information CAS Number: 85700 55 6
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