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1 μM and 27 μM
Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the Ca(2+)-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing
287(25):21067-81
CAS Number: 130641-38-2
17)10-4-2-8(12)3-5-10/h2-7H
E-3810 - CAS# 1058137-23-7 04995274 1 μM and 27 μMLucitanib , also known as E 3810 and AL3810, is a novel dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs) with antiangiogenic activity. VEGFR FGFR dual kinase inhibitor E 3810 inhibits VEGFR 1, 2, 3 and FGFR 1, 2 kinases in the nM range, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both
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