BYK 191023 dihydrochloride Catalog No.:M22335-C 2-fold higher than the values

2-fold higher than the values for dolastatin 10

2009 Jun 11

CCS(=O)(=O)C1=CC=C(C=N1)OC1C=C(C=C(C=1)O[C@@H](C)CO)C(=O)NC1C=CN(C)N=1

at hydroxylation sites in the oxygen-dependent degradation domain (ODDD)

5'-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA

BYK 191023 dihydrochloride Catalog No.:M22335-C 2-fold higher than the valuesIC50: 86 nM for iNOS NO synthases are enzymes responsible for the generation of nitric oxide from the amino acid L arginine. Once expressed the inducible NO synthase (iNOS) is active and produces M concentrations of NO over longer periods. The iNOS expression is stimulated in various cells by proinflammatory signals and is involved in immune defense. BYK191023 is a selective inhibitor of the inducible nitric oxide synthase (NOS). In vitro: BYK191023