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ClH/c28-21(17-18-7-2-1-3-8-18)26(38)34-16-5-4-10-23(34)25(37)33-22(9-6-15-31-27(29)30)24(36)32-19-11-13-20(14-12-19)35(39)40
selective and ATP competitive inhibitor of JAK3
BX471 (20 mg/kg
InChi: InChI=1S/C20H16ClN5O3/c1-22-19(27)16-10-12(6-8-23-16)11-29-20-17-15(7-9-28-17)18(25-26-20)24-14-4-2-13(21)3-5-14/h2-10H
In the rat model of status epilepticus (SE)
PD-1-IN-17 TFA Size:Contact [email protected] for quotation ClH/c28-21(17-18-7-2-1-3-8-18)26(38)34-16-5-4-10-23(34)25(37)33-22(9-6-15-31-27(29)30)24(36)32-19-11-13-20(14-12-19)35(39)40PD 1 IN 17 TFA is a programmed cell death 1 (PD 1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM. Product information Molecular Weight: 488. 37 Formula: C15H23F3N6O9 Chemical Name: (2S) 2 ({[(1S) 1 {5 [(1S,2R) 1 amino 2 hydroxypropyl] 1,3,4 oxadiazol 2 yl} 3 carbamoylpropyl]carbamoyl}amino) 3 hydroxypropanoic acid; trifluoroacetic acid Smiles: