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KB-R7943 - CAS# 182004-65-5 60131 In a recent publication in

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In a recent publication in Cell Stem Cell

22(8):2963-7

Smiles: NC1=CC=CN=C1/C=N/NC(N)=S

Dihexa binds with high affinity to HGF and both dihexa and its parent compound Norleucine 1-AngIV induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF-dependent cell scattering

Isakoff SJ

KB-R7943 - CAS# 182004-65-5 60131 In a recent publication inKB R7943, CAS No. 182004 65 5, is a potent, selective inhibitor of the reverse mode of the Na+ Ca2+ exchanger (IC50 = 0. 7 M). KB R7943 does not modify secondary pathology in the thalamus following focal cerebral stroke in rats. KB R7943 blocks opening of the mitochondrial permeability transition pore. KB R7943 restores endothelium dependent relaxation induced by advanced glycosylation end products in rat aorta. KB R7943 inhibits high glucose induced

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