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(S)-Lisofylline Catalog No.:M22422-C Solubility: DMSO : ≥ 100

SKU: 61704521958

4.6
USD100.00 USD147.00

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Description

Solubility: DMSO : ≥ 100 mg/mL (301

10a-tetramethyl-hexadecahydro-1H-spiro[chrysene-2

potent and orally active γ-secretase modulator (GSM)

In addition to CLK1

with 50 nM PU-H71 needed to significantly reduce the LPS dependent nitrite release

(S)-Lisofylline Catalog No.:M22422-C Solubility: DMSO : ≥ 100Lisofylline (LSF) is a potent anti inflammatory agent. LSF is a chiral metabolite of pentoxifylline . Pentoxifylline is exclusively reduced to (S) LSF in the cytosol when metabolized by isolated human liver cells . In vitro: Lisofylline preserved cell insulin secretion and inhibited DNA damage of islets in the presence of IL 1 . Simultaneous application of LSF and cytokines to INS 1 cells restored insulin secretion, mitochondrial membrane potential,

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