Pay in 4 interest-free payments of $22.25 Learn more
Ships within 48 hours · Estimated delivery Aug 9 - Aug 14
It inhibits LSD1 in biochemical assay with an IC50 ~16 nM
3-dioxygenase (IDO1) inhibitor with IC50 ~10 nM It displays high selectivity over other related enzymes such as IDO2 or tryptophan 2
Thiemermann C
EPZ-6438 was orally dosed to mice at 250-500 mg/kg twice per day for 21-28 days
A Potent and Selective MEK 1/2 Inhibitor
GSK-LSD1 - LSD1 Inhibitor. CAS# 2102933-95-7 0073 It inhibits LSD1 in biochemicalGSK LSD1, CAS No. 2102933 95 7, is a highly potent, specific and irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~16 nM, and is > 1000 fold selective over other closely related FAD utilizing enzymes (i. e. LSD2, MAO A, MAO B). GSK LSD1 induces gene expression changes in cancer cell lines (average EC50 < 5 nM) and inhibits cancer cell line growth (average EC50 < 5 nM). Product
US$ 232.00
US$ 55.00
US$ 312.50
US$ 128.50
US$ 232.00