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4]oxazepin-4(5H)-yl)propan-1-one
SK-MEL-2 and MeWo cells
InChi: InChI=1S/C33H33N3O15/c1-3-43-29(38)17-4-6-18(7-5-17)34-31(39)49-26-25(14-37)48-30(42-2)28(51-33(41)36-20-9-11-22-24(13-20)47-16-45-22)27(26)50-32(40)35-19-8-10-21-23(12-19)46-15-44-21/h4-13
PD153035 effectively blocks the enhancement of mitogenesis
Bassilana F
D-Sphingosine - CAS# 123-78-4 Catalog No.:M6801-10 4]oxazepin-4(5H)-yl)propan-1-oneD Sphingosine, CAS No. 123 78 4, is formed primarily from the breakdown of ceramide. Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase. D sphingosine, a lipid possessing the same hydrophobic base as ceramide but without a carbohydrate residue, efficiently blocked this glycolipid antigen presentation both in vitro and in spinal cords of EAE mice, and significantly decreased IL 17 and ameliorated the pathological symptoms.
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