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2017 Apr 3
Smiles: NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F
InChiKey: MDKGKXOCJGEUJW-UHFFFAOYSA-N
0 pM (-pIC50±SEM: 10
C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6
Atrasentan Hydrochloride K inhibitor 4 (trans) 2017 Apr 3Atrasentan, also known as ABT 627, is a orally available ETA receptor antagonist with potential antineoplastic activity. As a selective antagonist of the endothelin A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin induced angiogenesis and tumor cell proliferation. Product information CAS Number: 195733 43 8 Molecular Weight: 547. 08 Formula: C29H39ClN2O6 Chemical Name: (2R,3R,4S) 4 (2H
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