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tight-binding inhibitor of Escherichia coli LpxC with Ki=4 nM
and selective CVT-313 has no effect on other
5-dihydro-1H-pyrazol-1-yl)nicotinate
In breast cancer MDA-MB-231 and MDA-MB-468 cells
1337531-36-8
ICA-121431 TAC tight-binding inhibitor of Escherichia coliICA 121431 is a potent, selective inhibitor of the human Nav1. 3 and Nav1. 1 voltage gated sodium channels (IC50 = 19 nM) with little or no activity against human Nav1. 5 or Nav1. 7 channels. Voltage gated sodium channels initiate action potentials in brain neurons, and sodium channel blockers are used in therapy of epilepsy. Product information CAS Number: 313254 51 2 Molecular Weight: 449. 55 Formula: C23H19N3O3S2 Chemical Name: 2,2 diphenyl N {4
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