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ML364 induced an increase in cellular cyclin D1 degradation and caused cell cycle arrest as shown in Western blottings and flow cytometry assays utilizing both Mino and HCT116 cancer cell lines
and an increased escape latency of rats in the Morris water maze test
Solubility: DMSO: 60 mg/mL(198
is a potent and selective HDAC6 inhibitor with IC50 of 56 nM
4-Bis(1H-indol-3-yl)pyrrole-2
CX-4945 Sodium Salt zono)butane-1 3-dione ML364 induced an increase inCX 4945 Sodium Salt is a water soluble CX 4945 (GLXC 04060), First in class Casein kinase 2 (CK2) inhibitor, sequentially attenuating the proteins in PI3K Akt and MAPK pathways. Product information CAS Number: 1309357 15 0 Molecular Weight: 371. 75 Formula: C19H11ClN3NaO2 Synonym: Silmitasertib sodium salt Chemical Name: sodium 5 [(3 chlorophenyl)amino]benzo[c]2,6 naphthyridine 8 carboxylate Smiles: [Na+].[O
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