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This agent has little or no affinity for serotonin type 3 (5-HT3)
11aS)-1-hydroxy-11a-methyl-1-(prop-2-en-1-yl)-1H
ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35
Formula: C52H60F2N8O7
shifting excitation and emission maxima by 56 and 95 nm respectively
CHIR-98014 - CAS# 252935-94-7 Size:Solid 2 mg This agent has little orCHIR98014, also known as CT 98024, is a reversible, cell permeable inhibitor of GSK3 and GSK3 (IC50 = 0. 65 and 0. 58 nM, respectively). It is inactive against a series of other serine threonine or tyrosine kinases. Through its effects on GSK3, CHIR98014 stimulates glycogen synthase in cells (EC50 = 106 nM), potentiates insulin dependent glucose transport in isolated muscle strips, and improves glucose disposal in diabetic animals. CHIR98014 also
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