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114(2):1030-7
InChiKey: BGBNULCRKBVAKL-UHFFFAOYSA-N
Sildenafil citrate has been reported to decrease flap necrosis in preclinical animal models by increasing the secretion of growth factors (FGF and VEGF)
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VHL is one of the most popular E3 ligases being recruited by bifunctional PROTACs to induce ubiquitination and subsequent proteasomal degradation of a target protein
Raloxifene 6-glucuronide Catalog No.:M13237-10 114(2):1030-7Raloxifene 6 glucuronide is a primary metabolite of Raloxifene. Raloxifene 6 glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6 glucuronide binds to estrogen receptor with an IC50 of 290 M. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGF3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element containing vitellogenin promoter expression. Product
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