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PF-622 xy-2-phenethylchromone 5-trihydroxyoxan-2-yl 8

SKU: 74041685552

4.4
USD120.00 USD141.00

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Description

5-trihydroxyoxan-2-yl 8

0002) compare with untreated cultures at day 16

wtRyR1-HEK 293 pretreated with KB-R7943 (10 μM

6 nM and 98

PubMed PMID: 30660624

PF-622 xy-2-phenethylchromone 5-trihydroxyoxan-2-yl 8PF 622 is a potent, time dependent, irreversible FAAH inhibitor . Fatty acid amide hydrolase (FAAH), belongs to a member of an unusual class of serine hydrolases, is an integral membrane enzyme involved in regulating the fatty acid amide family of lipid transmitters. Genetic or pharmacological inactivation of FAAH leads to elevated endogenous levels of fatty acid amides with analgesic, anti inflammatory, anxiolytic, and antidepressant phenotypes. The

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