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identified by a high-throughput chemical screening for compounds that promote cell death in synergy with a small-molecule mimetic of Smac
the active component isolated from Tripterygium wilfordii Hook F
InChi: InChI=1S/C24H23N5O2/c1-15-12-18-17(22(25)30)8-5-9-21(18)29(15)24-27-20-10-11-31-14-19(20)23(28-24)26-13-16-6-3-2-4-7-16/h2-9
KARPAS-422 (Y641N) etc
101:104019
LY-2886721 - CAS# 1262036-50-9 size:2mg solid identified by a high-throughput chemicalLY2886721, CAS No. 1262036 50 9, is an BACE inhibitor used for the treatment of Alzheimer's Disease. IC50 value: Target: BACE LY2886721 is a novel potent agent that is used to treat Alzheimers Disease in preclinical experiments. LY2886721 is under clinical study. A Safety Study of LY2886721 Multiple Doses is performing in Healthy Subjects. Product information CAS Number: 1262036 50 9 Molecular Weight: 390. 41 Formula: C18H16F2N4O2S Chemical Name: N (3