N, N', N''-Triacetylchitotriose epristone BMS-345541 dose-dependently inhibits the TNF-α-stimulated

BMS-345541 dose-dependently inhibits the TNF-α-stimulated phosphorylation of IκBα in THP-1 monocytic cells with an IC50 of ~4 μM

into the brain

an ent-kauranoid diterpene from Rabdosia japonica var

3 nM) as ketanserin but with a much lower affinity for 5-HT2C sites (Ki= 620 nM)

34(6):912-918

N, N', N''-Triacetylchitotriose epristone BMS-345541 dose-dependently inhibits the TNF-α-stimulatedN,N',N'' Triacetylchitotriose is a competitive inhibitor of lysozyme. Product information CAS Number: 38864 21 0 Molecular Weight: 627. 59 Formula: C24H41N3O16 Chemical Name: N [(2R,3R,4S,5R) 4 {[(2S,3R,4R,5S,6R) 3 acetamido 5 {[(2S,3R,4R,5S,6R) 3 acetamido 4,5 dihydroxy 6 (hydroxymethyl)oxan 2 yl]oxy} 4 hydroxy 6 (hydroxymethyl)oxan 2 yl]oxy} 3,5,6 trihydroxy 1 oxohexan 2 yl]acetamide Smiles: