Futibatinib Catalog No.:M18482-C 4]triazine-1(6H)-carboxamide

4]triazine-1(6H)-carboxamide

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InChi: InChI=1S/C20H20N4O3S/c1-26-18-11-15(24-7-9-27-10-8-24)4-5-16(18)22-19(25)17-13-28-20(23-17)14-3-2-6-21-12-14/h2-6

Futibatinib Catalog No.:M18482-C 4]triazine-1(6H)-carboxamideFutibatinib (TAS 120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3. 9, 1. 3, 1. 6, and 8. 3 nM for FGFR 1 4, respectively. Futibatinib inhibits mutant and wild type FGFR2 with similar IC50s (wild type FGFR2=0. 9 nM; V5651=1 3 nM; N550H=3. 6 nM; E566G=2. 4 nM). Product information CAS Number: 1448169 71 8 Molecular Weight: 418. 45 Formula: C22H22N6O3 Chemical Name: 1 [(3S) 3 {4 amino 3 [2 (3,5