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Formula: C32H42N4O8S
97(5):567-72
One of the isotopic labelled form of Zopiclone
which inhibits ATR immunoprecipitated from HeLa nuclear extracts with an IC50 of 5 nM and ATR mediated phosphorylation of Chk1 in HT29 colorectal adenocarcinoma tumor cells with an IC50 of 50 nM
Formula: C23H30Cl3N5O3
Tozasertib - CAS# 639089-54-6 Size:Solid 2 mg Formula: C32H42N4O8STozasertib, also known as VX 680, MK0457 or VE465, is a synthetic, small molecule Aurora kinase inhibitor with potential antitumor activity. Tozasertib binds to and inhibits Aurora kinases (AKs), thereby inducing apoptosis in tumor cells in which AKs are overexpressed. AKs, a family of serine threonine kinases, are essential for mitotic progression, spindle formation, centrosome maturation, chromosomal segregation, and cytokinesis. Product information
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