TPA-023B )nitrosamine 52)53)36-28(46)19(8-9-23(38)39)34-30(48)21(13-25(42)43)35-26(44)15(3)33-27(45)18(32)12-24(40)41/h4-7

52)53)36-28(46)19(8-9-23(38)39)34-30(48)21(13-25(42)43)35-26(44)15(3)33-27(45)18(32)12-24(40)41/h4-7

10 and 20 μg/site) causes significant inhibition of glutamate-induced nociception in mice

55(36):10786-90

InChi: InChI=1S/C16H13BrF2N2O4

which has the common

TPA-023B )nitrosamine 52)53)36-28(46)19(8-9-23(38)39)34-30(48)21(13-25(42)43)35-26(44)15(3)33-27(45)18(32)12-24(40)41/h4-7TPA 023B is a high affinity and orally active GABAA receptor 2 3 subtype (Kis of 0. 73 nM 2 nM) partial agonist and a 1 subtype (Ki of 1. 8 nM) antagonist. TPA 023B has non sedating anxiolytic like properties. Product information CAS Number: 425377 76 0 Molecular Weight: 391. 37 Formula: C21H15F2N5O Chemical Name: 2',6 difluoro 5' [3 (2 hydroxypropan 2 yl)imidazo[1,2 b][1,2,4]triazin 7 yl] [1,1' biphenyl] 2 carbonitrile Smiles: