PF-04634817 Catalog No.:M21127-C Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(N[C@H]2CN(CCCCCCCNC(=O)COC3=CC=CC4C(=O)N(C5CCC(=O)NC5=O)C(=O)C=43)CCC2)=NC=C1Cl

Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(N[C@H]2CN(CCCCCCCNC(=O)COC3=CC=CC4C(=O)N(C5CCC(=O)NC5=O)C(=O)C=43)CCC2)=NC=C1Cl

KU14R does not act as an antagonist of either efaroxan or S22068 at an imidazoline site in vivo

Smiles: C[C@H]1COC2(CCN(CC2)C2=NC(=O)C3=CC(=CC(=C3S2)[N+]([O-])=O)C(F)(F)F)O1

Formula: C29H29ClN4O2

synthesis and characterization of process related desfluoro impurity of ezetimibe and HPLC method validations

PF-04634817 Catalog No.:M21127-C Smiles: CC(C)S(=O)(=O)C1=CC=CC=C1NC1=NC(N[C@H]2CN(CCCCCCCNC(=O)COC3=CC=CC4C(=O)N(C5CCC(=O)NC5=O)C(=O)C=43)CCC2)=NC=C1ClPF 0463481 is a potent and orally active dual CCR2 CCR5 antagonist with comparable human and rodent CCR2 potency (rat IC50=20. 8 nM), and displays 10 20 fold less rodent CCR5 potency (rat IC50=470 nM). PF 0463481 is safe and well tolerated and has the potential for the study of diabetic nephropathy. Product information CAS Number: 1228111 63 4 Molecular Weight: 511. 58 Formula: C25H36F3N5O3 Chemical Name: (3S,4S) 3 methoxy N [(1R,3S) 3 (propan 2 yl) 3