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Afuresertib HCl - CAS# 1047645-82-8 Catalog No.:M6857-2 Antidepressant Effects of (+)-MK-801 and

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Description

Antidepressant Effects of (+)-MK-801 and (-)-MK-801 in the Social Defeat Stress Model

1245792-51-1

PubMed PMID: 26413751

specifically HDAC 1

2020 Sep 1:S0161-6420(20)30844-7

Afuresertib HCl - CAS# 1047645-82-8 Catalog No.:M6857-2 Antidepressant Effects of (+)-MK-801 andAfuresertib HCl, CAS No. 1047645 82 8, also known as GSK2110183, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is

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